Nutrition Research
Volume 21, Issue 1 , Pages 199-213 , January 2001

Effect of red palm olein on bone tissue fatty acid composition and histomorphometric parameters☆1

  • Bruce A Watkins

      Affiliations

    • Department of Food Science, Lipid Chemistry and Molecular Biology Laboratory, Purdue University, West Lafayette, IN 47907, USA
    • Department of Anatomy, School of Medicine, Indiana University, Indianapolis, IN 46202, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-765-494-5802; fax: +1-765-494-7953
    • ,
  • Yong Li

      Affiliations

    • Department of Food Science, Lipid Chemistry and Molecular Biology Laboratory, Purdue University, West Lafayette, IN 47907, USA
    • ,
  • Laura L Rogers

      Affiliations

    • Department of Food Science, Lipid Chemistry and Molecular Biology Laboratory, Purdue University, West Lafayette, IN 47907, USA
    • ,
  • Walter E Hoffmann

      Affiliations

    • College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    • ,
  • Yasuko Iwakiri

      Affiliations

    • Department of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO 80523, USA
    • ,
  • Kenneth G.D Allen

      Affiliations

    • Department of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO 80523, USA
    • ,
  • Mark F Seifert

      Affiliations

    • Department of Anatomy, School of Medicine, Indiana University, Indianapolis, IN 46202, USA

Received 21 October 2000 ,Accepted 24 October 2000.

References 

  1. Atkinson TG, Barker HJ, Meckling-Gill KA. Incorporation of long-chain n-3 fatty acids in tissues and enhanced bone marrow cellularity with docosahexaenoic acid feeding in post-weanling Fischer 344 rats. Lipids. 1997;32:293–302
  2. Kokkinos PP, Shaye R, Alam BS, Alam SQ. Dietary lipids, prostaglandin E2 levels, and tooth movement in alveolar bone of rats. Calcif Tissue Int. 1993;53:333–337
  3. Watkins BA, Shen CL, Allen KG, Seifert MF. Dietary (n-3), and (n-6) polyunsaturates, and acetylsalicylic acid alter ex vivo PGE2 biosynthesis, tissue IGF-I levels, and bone morphometry in chicks. J Bone Miner Res. 1996;11:1321–1332
  4. Alam SQ, Kokkinos PP, Alam BS. Fatty acid composition and arachidonic acid concentrations in alveolar bone of rats fed diets with different lipids. Calcif Tissue Int. 1993;53:330–332
  5. Xu H, Watkins BA, Adkisson HD. Dietary lipids modify the fatty acid composition of cartilage, isolated chondrocytes and matrix vesicles. Lipids. 1994;29:619–625
  6. Moreau MF, Chappard D, Lesourd M, Montheard JP, Basle MF. Free radicals and side products released during methylmethacrylate polymerization are cytotoxic for osteoblastic cells. J Biomed Mater Res. 1998;40:124–131
  7. Hosoya S, Suzuki H, Yamamoto M, Kobayashi K, Abiko Y. Alkaline phosphatase and type I collagen gene expressions were reduced by hydroxyl radical-treated fibronectin substratum. Mol Genet Metab. 1998;65:31–34
  8. Suzuki H, Hayakawa M, Kobayashi K, Takiguchi H, Abiko Y. H2O2-derived free radicals treated fibronectin substratum reduces the bone nodule formation of rat calvarial osteoblast. Mech Ageing Dev. 1997;98:113–125
  9. Garrett IR, Boyce BF, Oreffo RO, Bonewald L, Poser J, Mundy GR. Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. J Clin Invest. 1990;85:632–639
  10. Passeri M, Provvedini D. Vitamin E in geriatric physiopathology. Acta Vitaminol Enzymol. 1983;5:53–63
  11. Xu H, Watkins BA, Seifert MF. Vitamin E stimulates trabecular bone formation, and alters epiphyseal cartilage morphometry. Calcif Tissue Int. 1995;57:293–300
  12. Watkins BA, Xu H, Turek JJ. Linoleate impairs collagen synthesis in primary cultures of avian chondrocytes. Proc Soc Exp Biol Med. 1996;212:153–159
  13. Park CK, Ishimi Y, Ohmura M, Yamaguchi M, Ikegami S. Vitamin A, and carotenoids stimulate differentiation of mouse osteoblastic cells. J Nutr Sci Vitaminol. 1997;43:281–296
  14. Tan B. Palm carotenoids, tocopherols and tocotrienols. J Am Oil Chem Soc. 1989;66:770–776
  15. Nesaretnam K, Stephen R, Dils R, Darbre P. Tocotrienols inhibit the growth of human breast cancer cells irrespective of estrogen receptor status. Lipids. 1998;33:461–469
  16. Nesaretnam K, Guthrie N, Chambers AF, Carroll KK. Effect of tocotrienols on the growth of a human breast cancer cell line in culture. Lipids. 1995;30:1139–1143
  17. Kamat JP, Sarma HD, Devasagayam TP, Nesaretnam K, Basiron Y. Tocotrienols from palm oil as effective inhibitors of protein oxidation and lipid peroxidation in rat liver microsomes. Mol Cell Biochem. 1997;170:131–137
  18. Kamat JP, Devasagayam TP. Tocotrienols from palm oil as potent inhibitors of lipid peroxidation and protein oxidation in rat brain mitochondria. Neurosci Lett. 1995;195:179–182
  19. Nanji AA, Zakim D, Rahemtulla A, Daly T, Miao L, Zhao S, et al. Dietary saturated fatty acids down-regulate cyclooxygenase-2 and tumor necrosis factor alfa and reverse fibrosis in alcohol-induced liver disease in the rat. Hepatology. 1997;26:1538–1545
  20. Zhang J, Ping W, Chunrong W, Shou CX, Keyou G. Nonhypercholesterolemic effects of a palm oil diet in Chinese adults. J Nutr. 1997;127:509S–513S
  21. Choudhury N, Tan L, Truswell AS. Comparison of palmolein and olive oil (effects on plasma lipids and vitamin E in young adults). Am J Clin Nutr. 1995;61:1043–1051
  22. Li Y, Seifert MF, Ney DM, Grahn M, Grant AL, Allen KG, et al. Dietary conjugated linoleic acids alter serum IGF-I and IGF binding protein concentrations and reduce bone formation in rats fed (n-6) or (n-3) fatty acids. J Bone Miner Res. 1999;14:1153–1162
  23. Seifert MF. Lack of evidence for rickets in the osteopetrotic rat mutation, toothless. J Bone Miner Res. 1994;9:1813–1821
  24. Watkins BA, Li Y, Allen KGD, Hoffmann WE, Seifert MF. Dietary ratio of (n-6)/(n-3) polyunsaturated fatty acids alters the fatty acid composition of bone compartments and biomarkers of bone formation in rats. J Nutr. 2000;130:2274–2284
  25. Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, et al. Bone histomorphometry (standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee). J Bone Miner Res. 1987;2:595–610
  26. Watkins BA, Shen CL, McMurtry JP, Xu H, Bain SD, Allen KG, et al. Dietary lipids modulate bone prostaglandin E2 production, insulin-like growth factor-I concentration and formation rate in chicks. J Nutr. 1997;127:1084–1091
  27. Hoffmann WE, Everds N, Pignatello M, Solter PF. Automated and semiautomated analysis of rat alkaline phosphatase isoenzymes. Toxicol Pathol. 1994;22:633–638
  28. Solter PF, Hoffmann WE, Chambers MD, Schaeffer DJ. CCK-8 infusion increases plasma LMW alkaline phosphatase coincident with enterohepatic circulation of bile acids. Am J Physiol. 1997;273:G381–G388
  29. Fligger JM, Malven PV, Doumit ME, Merkel RA, Grant AL. Increases in insulin-like growth factor binding protein-2 accompany decreases in proliferation and differentiation when porcine muscle satellite cells undergo multiple passages. J Anim Sci. 1998;76:2086–2093
  30. Iio H, Ake Y, Saegusa Y, Mizuno K. The effect of lipid peroxide on osteoblasts and vascular endothelial cells—the possible role of ischemia-reperfusion in the progression of avascular necrosis of the femoral head. Kobe J Med Sci. 1996;42:361–373
  31. Key LL, Ries WL, Taylor RG, Hays BD, Pitzer BL. Oxygen derived free radicals in osteoclasts (the specificity and location of the nitroblue tetrazolium reaction). Bone. 1990;11:115–119
  32. Suda N. Role of free radicals in bone resorption. J Stomatol Soc. 1991;58:603–612
  33. Imai T. The effects of long-term intake of restricted calcium, vitamin D, and vitamin E, and cadmium-added diets on the bone mass of mouse femoral bone (a microdensitometrical study). Jpn J Hygiene. 1995;50:754–762
  34. Melhus H, Michaelsson K, Holmberg L, Wolk A, Ljunghall S. Smoking, antioxidant vitamins, and the risk of hip fracture. J Bone Miner Res. 1999;14:129–135
  35. Isler O, Gutmann H, Solms U. Carotenoids. Basel, Stuttgart: Birkhäuser-Verlag; 1971;
  36. Rodriguez-Amaya DB. Latin American food sources of carotenoids. Arch Latinoam Nutr. 1999;49:74S–84S
  37. Morton RA. Fat-soluble vitamins. NY: Pergamon Press; 1970;
  38. Ziegler RG. A review of epidemiologic evidence that carotenoids reduce the risk of cancer. J Nutr. 1989;119:116–122
  39. Riemersma RA, Wood DA, Macintyre CC, Elton RA, Gey KF, Oliver MF. Risk of angina pectoris and plasma concentrations of vitamins A, C, and E and carotene. Lancet. 1991;337:1–5
  40. Serbinova E, Choo M, Packer L. Distribution and antioxidant activity of a palm oil carotene fraction in rats. Biochem Int. 1992;28:881–886
  41. Yee JK, Ima-Nirwana S. Palm vitamin E protects against ferric-induced impairment of bone calcification. Asia Pac J Pharmaco. 1998;13:1–7
  42. Ima-Nirwana S, Kiftiah A, Sariza T, Gapor MT, Khalid BA. Palm vitamin E improves bone metabolism and survival rate in thyrotoxic rats. Gen Pharmacol. 1999;32:621–626
  43. Norazlina M, Ima-Nirwana S, Gapor MT, Khalid BAK. Palm vitamin E is comparable to alpha-tocopherol in maintaining bone mineral density in ovariectomised female rats. Exp Clin Endocrinol Diabetes. 2000;108:305–310
  44. Schreck R, Baeuerle PA. Assessing oxygen radicals as mediators in activation of inducible eukaryotic transcription factor NF-kappa B. Methods Enzymol. 1994;234:151–163
  45. Boyce BF, Xing L, Franzoso G, Siebenlist U. Required and nonessential functions of nuclear factor-kappa B in bone cells. Bone. 1999;25:137–139
  46. Suzuki YJ, Packer L. Inhibition of NF-kappa B DNA binding activity by alpha-tocopheryl succinate. Biochem Mol Biol Int. 1993;31:693–700
  47. Teitelbaum SL. Bone resorption by osteoclasts. Science. 2000;289:1504–1508
  48. Dunstan CR. Osteoprotegerin and osteoprotegerin ligand mediate the local regulation of bone resorption. Endocrinologist. 2000;10:18–26
  49. Elson CE. Tropical oils (nutritional and scientific issues). Crit Rev Food Sci Nutr. 1992;31:79–102
  50. Suarna C, Hood RL, Dean RT, Stocker R. Comparative antioxidant activity of tocotrienols and other natural lipid-soluble antioxidants in a homogeneous system, and in rat and human lipoproteins. Biochim Biophys Acta. 1993;1166:163–170
  51. Qureshi AA, Burger WC, Peterson DM, Elson CE. The structure of an inhibitor of cholesterol biosynthesis isolated from barley. J Biol Chem. 1986;261:10544–10550
  52. Qureshi AA, Bradlow BA, Brace L, Manganello J, Peterson DM, Pearce BC, et al. Response of hypercholesterolemic subjects to administration of tocotrienols. Lipids. 1995;30:1171–1177
  53. Manorama R, Rukmini C. Serum lipids of rats fed crude and refined palm oil in high cholesterol and cholesterol free diets. Nutr Res. 1992;12:S93–S103
  54. Niyongabo A, Youyou A, Leger CL, Descomps B, Ammouche A, Bellal M. Effects of dietary crude palm oil, fish oil and their association on cholesterol and lipoprotein constants in rats which could be beneficial in humans. Int J Vitam Nutr Res. 1999;69:330–336
  55. Chaturvedi PA, Chaturvedi A. Effect of feeding crude red palm oil (Elaeis guineensis) and grain amaranth (Amaranthus paniculatus) to hens on total lipids, cholesterol, PUFA levels and acceptability of eggs. Plant Foods Hum Nutr. 2000;55:147–157
  56. Mundy G, Garrett R, Harris S, Chan J, Chen D, Rossini G, et al. Stimulation of bone formation in vitro and in rodents by statins. Science. 1999;286:1946–1949
  57. Chan KA, Andrade SE, Boles M, Buist DSM, Chase GA, Donahue JG, et al. Inhibitors of hydroxymethylglutaryl-coenzyme A reductase and risk of fracture among older women. Lancet. 2000;355:2185–2188
  58. Kritchevsky D, Tepper SA, Kuksis A, Wright S, Czarnecki SK. Cholesterol vehicle in experimental atherosclerosis. 22. Refined, bleached, deodorized (RBD) palm oil, randomized palm oil and red palm oil. Nutr Res. 2000;20:887–892
  59. Small DM. The effects of glyceride structure on absorption and metabolism. Annu Rev Nutr. 1991;11:413–434
  60. Kritchevsky D. Effects of triglyceride structure on lipid metabolism. Nutr Rev. 1988;46:177–181
  61. Khosla P, Hayes KC. Dietary trans-monounsaturated fatty acids negatively impact plasma lipids in humans (critical review of the evidence). J Am Coll Nutr. 1996;15:325–339
  62. Maiorano G, Manchisi A, Salvatori G, Filetti F, Oriani G. Influence of multiple injections of vitamin E on intramuscular collagen and bone characteristics in suckling lambs. J Anim Sci. 1999;77:2452–2457

PII: S0271-5317(00)00292-X

doi: 10.1016/S0271-5317(00)00292-X

Nutrition Research
Volume 21, Issue 1 , Pages 199-213 , January 2001

Article Tools