Nutrition Research
Volume 23, Issue 1 , Pages 111-116 , January 2003

FSH, TSH, T3 and T4 changes in relation to plasma copper and zinc alterations during D-penicillamine administration in female Wistar rats

  • George Tsanadis

      Affiliations

    • Obstetrics and Gynecology Department, University Hospital of Ioannina, Ioannina, Greece
    • Corresponding Author InformationCorresponding author. Tel.: +306510 99609.
    • ,
  • Alexandros Sotiriadis

      Affiliations

    • Obstetrics and Gynecology Department, University Hospital of Ioannina, Ioannina, Greece
    • ,
  • Patra Vezyraki

      Affiliations

    • Experimental Physiology Laboratory, University of Ioannina, Ioannina, Greece
    • ,
  • Vasiliki Kalfakakou

      Affiliations

    • Experimental Physiology Laboratory, University of Ioannina, Ioannina, Greece
    • ,
  • Konstantinos Zikopoulos

      Affiliations

    • Obstetrics and Gynecology Department, University Hospital of Ioannina, Ioannina, Greece
    • ,
  • Nicolaos Dalkalitsis

      Affiliations

    • Obstetrics and Gynecology Department, University Hospital of Ioannina, Ioannina, Greece
    • ,
  • Angelos Evangelou

      Affiliations

    • Experimental Physiology Laboratory, University of Ioannina, Ioannina, Greece
    • ,
  • Theodor Stefos

      Affiliations

    • Obstetrics and Gynecology Department, University Hospital of Ioannina, Ioannina, Greece

Received 19 December 2001 ,Revised 15 August 2002 ,Accepted 18 August 2002.

References 

  1. Bordin D, Sartorelli L, Bonanni G, Mastrogiacomo I, Scalco E. High intensity physical exercise induced effects on plasma levels of copper and zinc. Biol Trace Elem Res. 1993;36:129–134
  2. Vu S, Beynen AC. The combined effect of high iron and zinc intake on copper status in rats. Biol Trace Elem Res. 1994;42:71–80
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  11. Kochman K, Gajewska A, Kochman H, Kozlowski H, Masiukiewicz E, Rzeszotarska B. Binding of Cu2+, Zn2+, and Ni2+-GnRH Complexes with the Rat Pituitary Receptor. J Inorg Biochem. 1997;65:277–279
  12. Domingo JL, Gomez M, Jones MM. Concurrent administration of D-penicillamine and zinc has no advantages over the use of either single agent on copper excretion in the rat. Toxicology. 1998;126:195–201
  13. Kralik A, Kirchgessner M, Eder K. Concentrations of thyroid hormones in serum and activity of hepatic 5′monodeiodinase in copper deficient rats. Zeit Fur Ery. 1996;35:288–291
  14. Kralik A, Eder K, Kirchgessner M. Influence of zinc and selenium deficiency on parameters relating to thyroid hormones metabolism. Horm Metab Res. 1996;28:223–226
  15. Gonzalez Pondal M, Paier B, Noli MI, Tudino MB, Stripeikis JD, Hagmueller K, et al. Changes induced by zinc on thyroxine deiodination in rat liver in vivo and in vitro. Acta Physiol Pharmacol Ther Latinoamericana. 1995;45:35–41
  16. Olivieri O, Girelli D, Stanzial AM, Rossi L, Basi A, Corrocher R. Selenium, zinc, and thyroid hormones in healthy subjects (low T3/T4 ratio in the elderly is related to impaired selenium status). Biol Trace Elem Res. 1996;51:31–34
  17. Goel A, Dhawan D, Kheruka S. Evaluation of zinc in the regulation of serum T3 and T4 levels and hepatic functions in carbontetrachloride-intoxicated rats. Biol Trace Elem Res. 1994;41:59–68
  18. Nishiyama S, Futagoishi-Suginahara Y, Matsukura M, Nakamura T, Higashi A, Shinohara M, Matsuda I. Zinc supplementation alters thyroid hormone metabolism in disabled patients with zinc deficiency. J Am Col Nutr. 1994;13:62–67

PII: S0271-5317(02)00480-3

Nutrition Research
Volume 23, Issue 1 , Pages 111-116 , January 2003

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