Nutrition Research
Volume 23, Issue 10 , Pages 1417-1425 , October 2003

Effect of arginine and lysine on mitochondrial function during isoproterenol induced myocardial infarction in rats

  • Kesavarao Kumar Ebenezar

      Affiliations

    • Department of Biochemistry and Molecular Biology, University of Madras, Guindy Campus, Chennai-600 025, India
  • ,
  • Venkatachalem Sathish

      Affiliations

    • Department of Biochemistry and Molecular Biology, University of Madras, Guindy Campus, Chennai-600 025, India
  • ,
  • Thiruvengadam Devaki

      Affiliations

    • Department of Biochemistry and Molecular Biology, University of Madras, Guindy Campus, Chennai-600 025, India
    • Corresponding Author InformationCorresponding author. Tel.: +91-44-22351269; fax: +91-44-22352494.

Received 18 February 2003 ,Revised 2 June 2003 ,Accepted 2 June 2003.

References 

  1. Burton KP, McCord JM, Ghai G. Myocardial alterations due to free-radical generation. Am J Physiol. 1984;246:H776–H783
  2. Sushamakumari S, Jayadeep A, Sureshkumar JS, Menon VP. Effects of carnitine on malondialdehyde, taurine, glutathione levels in heart of rats subjected to myocardial stress by isoproterenol. Ind J Exp Biol. 1989;27:134–138
  3. Todd GL, Cullan GE, Cullan GM. Isoproterenol-induced myocardial necrosis and membrane permeability alterations in the isolated perfused rabbit heart. Exp Mol Pathol. 1980;33:43–54
  4. Chein KR, Abrams J, Serroni A, Martin JT, Farber JL. Accelerated phospholipid degradation and associated membrane dysfunction in irreversible, ischaemic liver cell injury. J Biol Chem. 1978;253:4809–4817
  5. Visek WJ. Arginine needs, physiological state and usual diets. A reevaluation. J Nutr. 1986;116:36–46
  6. Palmer RMJ, Ashton DS, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature. 1988;333:664–666
  7. Thomas S, Anup R, Susama P, Balasubramaniam KA. Nitric oxide prevents intestinal mitochondrial dysfunction induced by surgical stress. Br J Surg. 2001;88:393–399
  8. West ES, Todd WR, Mason HR, Van Bruggen JT. Amino acids. In:  West ES,  Todd WR editor. Text Book of Biochemistry. 4th edn. New Delhi: Oxford and IBH Publishing Company Private Limited; 1996;p. 1143–1263
  9. Egan JM, Henderson TE, Bernier M. Arginine enhances glycogen synthesis in response to insulin in 3T3-L1 adipocytes. Am J Physiol. 1995;265:E61–E66
  10. Kato T, Sano M, Muzutani N. Inhibitory effect of intravenous lysine infusion on urea cycle metabolism. Eur J Paediatr. 1987;146:56–58
  11. Sathish V, Vimal V, Ebenezar KK, Devaki T. Synergistic effect of nicorandil and amlodipine on mitochondrial function during isoproterenol-induced myocardial infarction in rats. J Pharm Pharmacol. 2002;54:133–137
  12. Johnson D, Lardy H. Isolation of liver or kidney mitochondria. In:  Estabrook RW editors. Methods in enzymology, Vol. 10. London: Academic Press; 1967;p. 94–96
  13. King J. Isocitrate dehydrogenase. In:  King JC,  Van D editor. Practical clinical enzymology. London: Nostrand Co; 1965;p. 363
  14. Mehler AH, Kornberg A, Crisolia S, Ochoa S. The enzymatic mechanism of oxidation reductions between malate or isocitrate or pyruvate. J Biol Chem. 1948;174:961–977
  15. Slater EC, Bonner WD. The effect of fluoride on the succinic oxidase system. Biochem J. 1952;52:185–196
  16. Reed LJ, Mukherjee RB. α-Ketoglutarate dehydrogenase complex from Escherichia coli. In:  Lowenstein JM editors. Methods in enzymology, Vol. 13. London: Academic Press; 1969;p. 53–61
  17. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979;95:351–358
  18. Pearl W, Cancercao J, Zweifach BW. Micro-determination of cytochrome oxidase in rat tissues by the oxidation on N-phenyl-p-phenylenediamine or ascorbic acid. J Histochem Cytochem. 1963;11:102–104
  19. Minaakami S, Ringler RL, Singer TP. Studies on the respiratory chain-linked dihydrodiphospho pyridine nucleotide dehydrogenase. Assay of the enzyme in particulate and insoluble preparations. J Biol Chem. 1962;237:569–576
  20. Williamson JR, Corkery BE. In:  Lowenstein JM editors. Methods in Enzymology, Vol. 13. New York: Academic Press; 1969;p. 488–491
  21. Ballentine R, Burford DD. Determination of metals. In:  Colowick SP,  Kalpan NO editor. Methods in Enzymology, Vol. 3. New York: Academic Press; 1957;p. 1002–1035
  22. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with Folin-phenol reagent. J Biol Chem. 1951;193:265–275
  23. King J. The dehydrogenase of oxido reductase-lactate dehydrogenase. In:  King JC,  Van D editor. Practical Clinical Enzymology. London: Nostrand Co; 1965;p. 83–93
  24. Okinaka S, Kumogai H, Ebashi S, Sugita H, Momoi H, Toyokura Y, et al. Serum creatine phosphokinase activity in progressive muscular dystrophy and neuro muscular diseases. Arch Neurol. 1961;4:520–525
  25. Bergmeyer HV, Bernt E. Amino transferases and related enzymes. In:  Bergmeyer HV editors. Methods of enzymatic analysis, Vol. 2. New York: Academic Press; 1974;p. 735–763
  26. Hearse DJ. Cellular damage during myocardial ischaemia: metabolic changes leading to enzyme leakage. In:  Hearse DJ,  De leiris J,  Loisance D editor. Enzymes in Cardiology. New York: John Wiley and Sons Ltd; 1979;p. 1–21
  27. Mathew S, Menon RVG, Kurup PA. Effect of administration of vitamin A, ascorbic acid and nicotinamide adenine dinucleotide + flavin adenine nucleotide on severity of myocardial infarction induced by isoproterenol in rats. Ind J Biol. 1985;23:500–504
  28. Sree Priya M, Saravanan N, Devaki T, Nayeem M. Protective effect of L-arginine on experimental myocardial injury by β-adrenergic stimulation in rats. J Clin Biochem Nutr. 1999;27:19–26
  29. Smulders RA, Aarsen M, Teerlink T, De Vries PM, Van Kamp GJ, Donker AJ, et al. Haemodynamic and biochemical responses to L-arginine and L-lysine infusions in normal subjects (L-arginine-induced vasodilatation cannot be explained by non-specific effects of cationic amino acids). Clin Sci (Lond). 1997;92:367–374
  30. Kanner J, Harel S, Granit R. Nitric oxide as an antioxidant. Arch Biochem Biophys. 1991;289:130–136
  31. Comporti M. Lipid peroxidation and cellular damage in toxic liver injury. Lab Invest. 1985;53:599–623
  32. Fang FC. Mechanisms of nitric oxide related antimicrobial activity. J Clin Invest. 1977;99:2818–2825
  33. Goss SPA, Hogg N, Kalyanaraman B. The antioxidant effect of spermine NONOate in human low density lipoprotein. Chem Res Toxicol. 1995;8:800–806
  34. Rubbo H, Radi R, Trujillo M, Telleri R, Kalyanaraman B, Barnes S, et al. Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen containing lipid derivatives. J Biol Chem. 1994;269:26066–26075
  35. Node K, Kitakaze M, Sato M, Minamino T, Komamura K, Shinozaki Y, et al. Role of intracellular Ca2+ in activation of protein kinase c during ischemic preconditioning. Circ. 1997;96:1257–1265
  36. Hearse DJ. Reperfusion of the ischemic myocardium. J Mol Cell Cardiol. 1977;9:605–616
  37. Osmundsen H. Peroxisomal β-oxidation of long chain fatty acids (effects of high fat diets). Ann N Y Acad Sci. 1982;386:13–29
  38. Thyagarajan B, Malli R, Schmidt K, Graier WF, Groschner K. Nitric oxide inhibits capacitative Ca2+ entry by suppression of mitochondrial Ca2+ handling. Br J Pharmacol. 2002;137:821–830
  39. Jikko A, Taki Y, Nakamura N, Tanaka J, Kamiyama Y, Ozawa KJ, et al. Adenylate energy change and cytochrome a(+a3) in the cirrhotic rat liver. Surg Res. 1984;37:361–368
  40. Regitz V, Azumi T, Stephen H, Naujooks S, Schaper W. Biochemical mechanism of infarct size reduction by pyruvate. Cardiovasc Res. 1981;15:652–658
  41. Calva E, Mujica A, Nunez R, Aoki K, Bisteni A, Sodi-Pallares D. Mitochondrial biochemical changes and glucose-KCl-insulin solution in cardiac infarct. Am J Physiol. 1966;211:71–76
  42. Vijayapadma V, Shyamaladevi CS. Effect of fish oil on mitochondrial respiration in isoproterenol induced myocardial infarction in rats. Ind J Exp Biol. 2001;40:268–272

PII: S0271-5317(03)00234-3

doi: 10.1016/S0271-5317(03)00234-3

Nutrition Research
Volume 23, Issue 10 , Pages 1417-1425 , October 2003