Nutrition Research
Volume 24, Issue 5 , Pages 373-381, May 2004

Antidiabetic influence of quercetin in streptozotocin-induced diabetic rats

  • A.K Shetty

      Affiliations

    • Department of Biochemistry and Nutrition, Central Food Technological Research Institute, Mysore 570 013, India
    • ,
  • R Rashmi

      Affiliations

    • Department of Biochemistry and Nutrition, Central Food Technological Research Institute, Mysore 570 013, India
    • ,
  • M.G.R Rajan

      Affiliations

    • Radiation Medicine Centre, Jerbhai Wadia Road, Parel, Mumbai 400 012, India
    • ,
  • K Sambaiah

      Affiliations

    • Department of Biochemistry and Nutrition, Central Food Technological Research Institute, Mysore 570 013, India
    • ,
  • P.V Salimath

      Affiliations

    • Department of Biochemistry and Nutrition, Central Food Technological Research Institute, Mysore 570 013, India
    • Corresponding Author InformationCorresponding author. Tel.: +91-821-2514876; fax: +91-821-2517233.

Received 16 June 2003; received in revised form 29 October 2003; accepted 27 November 2003.

Abstract 

The effect of feeding quercetin at the level of 1 g per kilogram of diet was studied in rats with streptozotocin-induced diabetes. The study involved a comparison between a starch-fed diabetic group and quercetin-fed diabetic group. The rats were examined for diet intake, water intake, gain in body weight, urine output, urine sugar, and fasting blood sugar. Diabetic status in rats was found to be ameliorated about 25% in rats fed with quercetin.

Keywords:  Diabetes, Quercetin, Urine sugar, Urine volume, Fasting blood sugar

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PII: S0271-5317(04)00038-7

doi:10.1016/j.nutres.2003.11.010

Nutrition Research
Volume 24, Issue 5 , Pages 373-381, May 2004

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