Nutrition Research
Volume 24, Issue 11 , Pages 909-921 , November 2004

The effect of reduced maternal protein intake during pregnancy on placental lipid composition in the rat: effect of glycine supplementation of the low protein diet

Received 7 November 2003 ,Revised 28 May 2004 ,Accepted 2 June 2004.

References 

  1. Catalano PM, Thomas AJ, Huston LP, Fung CM. Effect of maternal metabolism on fetal growth and body composition. Diabetes Care. 1998;21(Suppl. 2):B85–B90
  2. Barker DJ. In utero programming of chronic disease. Clin. Sci. 1998;95:115–128
  3. Godfrey KM. Maternal regulation of fetal development and health in adult life. Eur. J. Obstet. Gynecol. Reprod. Biol. 1998;78:141–150
  4. Leaf AA, Leighfield MJ, Costeloe KL, Crawford MA. Long chain polyunsaturated fatty acids and fetal growth. Early Hum. Dev. 1992;30:183–191
  5. Innis SM. The role of dietary n-6 and n-3 fatty acids in the developing brain. Dev. Neurosci. 2000;22:474–480
  6. Chambaz J, Ravel D, Manier MC, Pepin D, Mulliez N, Bereziat G. Essential fatty acid interconversion in the human fetal liver. Biol. Neonate. 1985;47:136–140
  7. Ravel D, Chambaz J, Pepin D, Manier MC, Bereziat G. Essential fatty acid interconversion during gestation in the rat. Biochim. Biophys. Acta. 1985;833:161–164
  8. Cho HP, Nakamura M, Clarke SD. Cloning, expression, and fatty acid regulation of the human delta-5 desaturase. J. Biol. Chem. 1999;274:37335–37339
  9. Ministry of Agriculture, Fisheries and Food. Food information surveillance sheet 127. Dietary intake of iodine and fatty acids. Lonton: Ministry of Agriculture, Fisheries and Food; 1997;
  10. Kris-Etherton PM, Shaffer Taylor D, Yu-Poth S, Huth P, Moriarty K, Fishell V, et al. Polyunsaturated fatty acids in the food chain in the United States. Am. J. Clin. Nutr. 2000;71:179–188
  11. Reeves PG, Nielsen FH, Fahey GC. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J. Nutr. 1993;123:1939–1951
  12. Sprecher H, Chen Q, Yin FQ. Regulation of the biosynthesis of 22:5n-6 and 22:6n-3: a complex intracellular process. Lipids. 1999;34:153–156
  13. Langley SC, Jackson AA. Increased systolic blood pressure in adult rats induced by foetal exposure to maternal low protein diet. Clin. Sci. 1994;86:217–222
  14. Langley-Evans SC, Phillips GJ, Benediktsson R, Gardner DS, Edwards CR, Jackson AA, et al. Protein intake in pregnancy, placental glucocorticoid metabolism and the programming of hypertension in the rat. Placenta. 1996;17:169–172
  15. Itoh S, Brawley L, Wheeler T, Anthony FW, Poston L, Hanson MA. Vasodilation to vascular endothelial growth factor in the uterine artery of the rat is blunted by low dietary protein intake. Pediatr. Res. 2002;51:485–491
  16. Doherty CB, Lewis RM, Sharkey A, Burton GJ. Placental composition and surface area but not vascularisation are altered by maternal protein restriction in the rat. Placenta. 2003;24:34–38
  17. Rosso P. Maternal–fetal exchange during protein malnutrition in the rat. Placental transfer of alpha-amino isobutyric acid. J. Nutr. 1977;107:2002–2005
  18. Rosso P. Maternal–fetal exchange during protein malnutrition in the rat. Placental transfer of glucose and a nonmetabolizable glucose analog. J. Nutr. 1977;107:2006–2010
  19. Burdge GC, Dunn RL, Wootton SA, Jackson AA. Effect of reduced dietary protein intake on hepatic and plasma essential fatty acid concentrations in the adult female rat: effect of pregnancy and consequences for accumulation of arachidonic and docosahexaenoic acids in fetal liver and brain. Br. J. Nutr. 2002;88:379–387
  20. Burdge GC, Delang E, Dubois L, Dunn RL, Hanson MA, Jackson AA, et al. Effect of reduced maternal protein intake in pregnancy in the rat on the fatty acid composition of brain, liver, plasma, heart and lung phospholipids of the offspring after weaning. Br. J. Nutr. 2003;90:345–352
  21. Ozanne SE, Martinsz ND, Petry CJ, Loizou CL, Hales CN. Maternal low protein diet in rats programmes fatty acids desaturase activities in the offspring. Diabetologica. 1998;41:1337–1342
  22. Kuhn DC, Crawford M. Placental essential fatty acid transport and prostaglandin synthesis. Prog. Lipid Res. 1986;25:345–353
  23. Rees WD, Hay SM, Buchan V, Antipatis C, Palmer RM. The effects of maternal protein restriction on the growth of the rat fetus and its amino acid supply. Br. J. Nutr. 1999;81:243–250
  24. Jackson AA. Maternal and fetal demands for nutrients: significance of protein metabolism. In:  O'Brain PMS,  Wheeler T,  Barker DJP editor. Fetal programming: influences of development and disease in later life. London: Royal College of Obstetricians and Gynaecologists Press; 1999;p. 246–270
  25. Jackson AA. Salvage of urea-nitrogen and protein requirements. Proc. Nutr. Soc. 1995;54:535–547
  26. Jackson AA, Shaw JC, Barber A, Golden MH. Nitrogen metabolism in preterm infants fed human donor breast milk: the possible essentiality of glycine. Pediatr. Res. 1981;15:1454–1461
  27. Jackson AA, Dunn RL, Marchand MC, Langley-Evans SC. Increased systolic blood pressure in rats induced by a maternal low-protein diet is reversed by dietary supplementation with glycine. Clin. Sci. 2002;103:633–639
  28. Folch J, Lees M, Sloane-Stanley GH. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 1957;226:497–509
  29. Burdge GC, Wright P, Jones AE, Wootton SA. A method for separation of phosphatidylcholine, triacylglycerol, non-esterified fatty acids and cholesterol esters from plasma by solid phase extraction. Br. J. Nutr. 2000;84:781–787
  30. Burdge GC, Hunt AD, Postle AD. Mechanisms of hepatic phosphatidylcholine synthesis in adult rat: effects of pregnancy. Biochem. J. 1994;303:941–947
  31. Larque E, Garcia-Ruiz PA, Perez-Llamas F, Zamora S, Gil A. Dietary trans fatty acids alter the compositions of microsomes and mitochondria and the activities of microsome Δ6-fatty acid desaturase and glucose-6-phosphatase in livers of pregnant rats. J. Nutr. 2003;133:2526–2531
  32. De Thomas ME, Mercuri O, Serres C. Effect of cross-fostering rats at birth on the normal supply of essential fatty acids during protein deficiency. J. Nutr. 1983;113:314–319
  33. Litman BJ, Mitchell DC. A role for phospholipid polyunsaturation in modulating membrane protein function. Lipids. 1996;31(Suppl.):S193–S197
  34. Mitchell DC, Straume M, Litman BJ. Role of sn-1 saturated, Sn-2 polyunsaturated phospholipids in control of membrane receptor conformational equilibrium: effects of cholesterol and acyl chain unsaturation on the metarhodopsin Iϕ metarhodopsin II equilibrium. Biochemistry. 1992;31:662–670
  35. Godfrey KM, Mattews N, Glazier J, Jackson A, Wilman C, Sibley CP. Neutral amino acid uptake by the microvillus plasma membrane of the human placenta is inversely related to fetal size at birth in normal pregnancy. J. Clin. Endocrinol. Metab. 1998;83:3320–3326
  36. Araya J, Soto C, Aguilera AM, Bosco C, Molina R. Modification of the lipid profile of human placenta by moderate maternal under nutrition. Rev. Med. Chile. 1994;22:503–509
  37. Coleman RA, Hayes ED. Microsomal and lysosomal enzymes of triacylglycerol metabolism in rat placenta. Biochem. J. 1984;217:391–397
  38. Coleman RA, Hayes EB. Synthesis and release of fatty acids by human trophoblast cells in culture. J. Lipid Res. 1987;28:1335–1341
  39. Diamant YZ, Diamant S, Freinkel N. Lipid deposition and metabolism in rat placenta during gestation. Placenta. 1980;1:319–325
  40. Groski J, Nowacka M. Effect of exposure to cold and fasting on the placental glycogen and triglyceride content in the rat. Arch. Gynecol. Obstet. 1989;244:151–155
  41. Campbell FM, Gordon MJ, Dutta-Roy AK. Preferential uptake of long-chain polyunsaturated fatty acids by isolated human placental membranes. Mol. Cell. Biochem. 1996;155:77–83
  42. Campbell FM, Clohessy AM, Gordon MJ, Page KR, Dutta-Roy AK. Uptake of long-chain fatty acids by human placental choriocarcinoma (BeWo) cells: role of plasma membrane fatty acid binding protein. J. Lipid Res. 1997;38:2558–2568
  43. Campbell FM, Gordon MJ, Dutta-Roy AK. Plasma membrane fatty acid binding protein from human placenta: identification and characterisation. Biochem. Biophys. Res. Comm. 2000;209:1011–1017
  44. Haggarty P, Pahe K, Abramovich DR, Ashton J, Brown D. Long-chain polyunsaturated fatty acid transport across the perfused human placenta. Placenta. 1997;18:635–642
  45. Knipp GT, Liu B, Audus KL, Fujii H, Ono T, Soares MJ. Fatty acid transport regulatory proteins in the developing rat placenta and in trophoblast cell culture models. Placenta. 2000;21:367–375
  46. Neuringer M, Connor WE, Van Petten C, Barstad L. Dietary omega-3 fatty acid deficiency and visual loss in infant rhesus monkeys. J. Clin. Invest. 1984;73:272–276
  47. Neuringer M, Connor WE, Lin DS, Barstad L, Luck S. Biochemical and functional effects of prenatal and postnatal omega-3 fatty acid deficiency on retina and brain in rhesus monkeys. Proc. Natl. Acad. Sci. USA. 1986;83:4021–4025
  48. Postle AD, Al MDM, Burdge GC, Hornstra G. The composition of individual molecular species of plasma phosphatidylcholine in human pregnancy. Early Hum. Dev. 1995;43:47–58

PII: S0271-5317(04)00120-4

doi: 10.1016/j.nutres.2004.06.007

Nutrition Research
Volume 24, Issue 11 , Pages 909-921 , November 2004

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