Assessment of the nutritional status of rats submitted to food restriction and/or to physical exercise

Pedrosa, Rogerio G.; Tirapegui, Julio; Rogero, Marcelo M.; de Castro, Inar A.; Pires, Ivanir S.O.; Salgado, Maristela M.; Ueda, Mirthes

doi:10.1016/j.nutres.2004.03.005

Next »Nutrition Research
Volume 24, Issue 11 , Pages 923-934, November 2004

Assessment of the nutritional status of rats submitted to food restriction and/or to physical exercise

Rogerio G. Pedrosa
- Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, 05508-900 São Paulo, SP, Brazil
Julio Tirapegui
- Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, 05508-900 São Paulo, SP, Brazil
- Corresponding author. Tel.: +5 11 3091 3309; fax: +5 11 3815 4410.
Marcelo M. Rogero
- Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, 05508-900 São Paulo, SP, Brazil
Inar A. de Castro
- Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, 05508-900 São Paulo, SP, Brazil
Ivanir S.O. Pires
- Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, 05508-900 São Paulo, SP, Brazil
Maristela M. Salgado
- Department of Immunology, Service of Microbiology and Immunology, Adolfo Lutz Institute, 01246-902 São Paulo, SP, Brazil
Mirthes Ueda
- Service of Microbiology and Immunology, Division of Medical Biology, Adolfo Lutz Institute, São Paulo, SP, Brazil

Received 15 October 2003; received in revised form 15 December 2003; accepted 18 March 2004.

Abstract

Objective

To assess the effect of some strategies for body weight reduction on the nutritional status of rats.

Methods and Materials

Thirty-six rats were divided into 6 equal groups: sedentary (S100), trained (T100), sedentary + 25% food restriction (FR) (S75), sedentary + 50% FR (S50), trained + 25% FR (T75), and trained + 50% FR (T50). Body composition and serum insulin-like growth factor-1, albumin, and IgG concentrations were determined and the delayed-type hypersensitivity test was applied.

Results

Insulin-like growth factor-1 (IGF-1) concentration was lower in the S50 group and higher in the T75 and T50 groups compared with the S100 group. The response to the delayed-type hypersensitivity and IgG concentrations were lower in the S50 and T50 groups; however, the difference was nonsignificant.