Nutrition Research
Volume 25, Issue 12 , Pages 1043-1048, December 2005

Zinc absorption from a micronutrient-fortified dried cow's milk used in the Chilean National Complementary Food Program

  • Manuel Ruz

      Affiliations

    • Department of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile
    • Corresponding Author InformationCorresponding author. Fax: +562 7378778.
  • ,
  • Juana Codoceo

      Affiliations

    • Department of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile
  • ,
  • Jorge Inostroza

      Affiliations

    • Department of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile
  • ,
  • Anabella Rebolledo

      Affiliations

    • Department of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile
  • ,
  • Nancy F. Krebs

      Affiliations

    • Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
  • ,
  • Jamie E. Westcott

      Affiliations

    • Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
  • ,
  • Lei Sian

      Affiliations

    • Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
  • ,
  • K. Michael Hambidge

      Affiliations

    • Section of Nutrition, Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA

Received 15 May 2005; received in revised form 30 August 2005; accepted 7 September 2005.

Abstract 

The objective was to compare the absorption of zinc from a micronutrient-fortified dried cow's milk, which is part of the Chilean National Complementary Food Program, with that from a standard nonfortified milk. Fortification included the addition of iron, zinc, copper, and ascorbic acid to provide total concentrations (in 100 g of powder) of 10, 5, 0.5, and 70 mg, respectively. Seven adults with normal plasma zinc concentrations (16.0 ± 0.9 μmol/L) were studied. Fractional absorption of zinc was determined from single test meals using a stable isotope–based methodology. Mean (± SD) fractional absorption of zinc of the test meal containing nonfortified milk was 0.29 ± 0.09 compared with 0.30 ± 0.09 of the test meal with the fortified milk (P = not significant). Absolute zinc absorptions from the test meals were 0.43 ± 0.14 vs 0.57 ± 0.16 mg, respectively (P = .02). Micronutrient fortification of dried cow's milk, including zinc, was associated with increased total zinc absorption.

Keywords: Zinc, Micronutrients, Milk, Food fortification, Humans

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PII: S0271-5317(05)00181-8

doi:10.1016/j.nutres.2005.09.009

Nutrition Research
Volume 25, Issue 12 , Pages 1043-1048, December 2005