Nutrition Research
Volume 28, Issue 2 , Pages 72-77 , February 2008

Pomegranate juice is potentially better than apple juice in improving antioxidant function in elderly subjects

Received 27 June 2007 ,Revised 29 November 2007 ,Accepted 2 December 2007.

References 

  1. Harman D. Aging: overview. Ann NY Acad Sci. 2001;928:1–21
  2. Sohal RS, Mockett RJ, Orr WC. Mechanisms of aging: an appraisal of the oxidative stress hypothesis. Free Radic Biol Med. 2002;33:575–586
  3. Bokov A, Chaudhuri A, Richardson A. The role of oxidative damage and stress in aging. Mech Ageing Dev. 2004;125:811–826
  4. Sohal RS, Weindruch R. Oxidative stress, caloric restriction, and aging. Science. 1996;273:59–63
  5. Priemé H, Loft S, Nyyssõnen K, Salonen JT, Poulsen HE. No effect of supplementation with vitamin E, ascorbic acid, or coenzyme Q10 on oxidative damage estimated by 8-ox-7,8-dihydro-2′-deoxyquanosine excretion in smokers. Am J Clin Nutr. 1997;65:503–507
  6. Zandi PP, Anthony JC, Khachaturian AS, Stone SV, Gustafson D, Tschanz TJ, et al. Reduced risk of Alzheimer disease in users of antioxidant vitamin supplements: the Cache County Study. Arch Neurol. 2004;61:82–88
  7. Petersen RC, Thomas RG, Grundman M, Bennett D, Doody R, Ferris S, et al. Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med. 2005;352:2379–2388
  8. Etminan M, Gill SS, Samii A. Intake of vitamin E, vitamin C, and carotenoids and the risk of Parkinson's disease: a meta-analysis. Lancet Neurol. 2005;4:362–365
  9. Guo CJ, Yang JJ, Wei JY, Li YF, Xu J, Jiang YG. Antioxidant activities of peel, pulp and seed fractions of common fruits as determined by FRAP assay. Nutr Res. 2003;23:1719–1726
  10. Guo CJ, Cao GH, Sofic E, Prior RL. High-performance liquid chromatography coupled with coulometric array detection of electroactive components in fruits and vegetables: relationship to oxygen radical absorbance capacity. J Agric Food Chem. 1997;45:1787–1796
  11. Cao GH, Russell RM, Lischner N, Prior RL. Serum antioxidant capacity is increased by consumption of strawberries, spinach, red wine or vitamin C in elderly women. J Nutr. 1998;128:2383–2390
  12. Verhagen H, Poulsen HE, Loft S, van Poppel G, Willems MI, Bladeren PJ. Reduction of oxidative DNA damage in humans by Brussels sprouts. Carcinogenesis. 1995;16:969–970
  13. Ko SH, Choi SW, Ye SK, Cho BL, Kim HS, Chung MH. Comparison of the antioxidant activities of nine different fruits in human plasma. J Med Food. 2005;8:41–46
  14. Xu J, Guo CJ, Yang JJ, Wei JY, Li YF, Pang W, et al. Intervention of antioxidant system function of aged rats by giving fruit juices with different antioxidant capacities. Chin J Prev Med. 2005;39:80–83
  15. Benzie IFF, Strain JJ. The ferric reducing ability of plasma as a measure of “antioxidant power”: the FRAP assay. Anal Biochem. 1996;239:70–76
  16. Brewster MA, Turley CP. Vitamin C. In:  Pesce AJ,  Kaplan LA editor. Methods in clinical chemistry. Mosby Company, St Louis: The CV; 1987;p. 574–581
  17. Hansen LG, Warwich WJ. An improved assay method for serum vitamin A and E using fluorometry. Am J Clin Pathol. 1978;70:922–923
  18. Ohkawa H, Ohishi N, Kunio Y. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979;95:351–358
  19. Levine RL, Garland D, Oliver CN, Amici A, Climent I, Lenz A, et al. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol. 1990;186:464–478
  20. Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res. 1988;175:184–191
  21. Langley P. Why a pomegranate?. BMJ. 2000;321:1153–1154
  22. Gil MI, Tomas-Barberan FA, Hess-Pierce B, Holcroft DM, Kader AA. Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J Agric Food Chem. 2000;48:4581–4589
  23. Aviram M, Dornfeld L, Rosenblat M, Volkova N, Kaplan M, Coleman R, et al. Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E–deficient mice. Am J Clin Nutr. 2000;71:1062–1076
  24. Kaplan M, Hayek T, Raz A, Coleman R, Dornfeld L, Vaya M, et al. Pomegranate juice supplementation to atherosclerotic mice reduces macrophage lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J Nutr. 2001;131:2082–2089
  25. Noda Y, Kaneyuki T, Mori A, Packer L. Antioxidant activities of pomegranate fruit extract and its anthocyanidins: delphinidin, cyanidin, and pelargonidin. J Agric Food Chem. 2002;50:166–171
  26. Manach C, Morand C, Texier O, Favier ML, Agullo G, Demigne C, et al. Quercetin metabolites in plasma of rats fed diets containing rutin or quercetin. J Nutr. 1995;125:1911–1922
  27. McAnlis GT, McEneny J, Pearce J, Young IS. Absorption and antioxidant effects of quercetin from onions in man. Eur J Clin Nutr. 1999;53:92–96
  28. Ader P, Wessmann A, Wolffram S. Bioavailability and metabolism of the flavonol quercetin in the pig. Free Radic Biol Med. 2000;28:1056–1067
  29. Su JF, Guo CJ, Wei JY, Yang JJ, Jiang YG, Li YF. Study on the absorption of quercetin and rutin at different segments of intestine. J Hygiene Res. 2002;31:55–57
  30. Su JF, Guo CJ, Wei JY, Yang JJ, Jiang YG, Li YF. Protection against hepatic ischemia-reperfusion injury in rats by oral pretreatment with quercetin. Biomed Environ Sci. 2003;16:1–8
  31. Cao GH, Muccitelli HU, Sánchez-Moreno C, Prior RL. Anthocyanins are absorbed in glycated forms in elderly women: a pharmacokinetic study. Am J Clin Nutr. 2001;73:920–926
  32. Mazza G, Kay CD, Cottrell T, Holub BJ. Absorption of anthocyanins from blue berries and serum antioxidant status in human subjects. J Agric Food Chem. 2002;50:7731–7737
  33. Kay CD, Mazza G, Holub B. Anthocyanins exit in the circulation primarily as metabolites in adult men. J Nutr. 2005;135:2582–2588
  34. Stadtman ER, Oliver CN, Levine RL, Fucci L, Rivett AJ. Implication of protein oxidation in protein turnover, aging and oxygen toxicity. Basic Life Sci. 1988;49:331–339
  35. Boulton DW, Walle KU, Walle T. Extensive binding of the bioflavonoid quercetin to human plasma proteins. J Pharm Pharmacol. 1998;50:243–249

PII: S0271-5317(07)00282-5

doi: 10.1016/j.nutres.2007.12.001

Nutrition Research
Volume 28, Issue 2 , Pages 72-77 , February 2008