Nutrition Research
Volume 29, Issue 2 , Pages 94-99 , February 2009

Depressed serum selenoprotein P: possible new predicator of increased risk for cerebrovascular events

  • Hiroshi Koyama

      Affiliations

    • Department of Public Health, Gunma University Graduate School of Medicine, 371-8511 Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81 27 220 8010; fax: +81 27 220 8016.
  • ,
  • Rizky Abdulah

      Affiliations

    • Department of Public Health, Gunma University Graduate School of Medicine, 371-8511 Japan
  • ,
  • Takayoshi Ohkubo

      Affiliations

    • Department of Planning for Drug Development and Clinical Evaluation, Tohoku University, Graduate School of Pharmaceutical Sciences and Medicine, 980-8575 Japan
  • ,
  • Yutaka Imai

      Affiliations

    • Department of Planning for Drug Development and Clinical Evaluation, Tohoku University, Graduate School of Pharmaceutical Sciences and Medicine, 980-8575 Japan
  • ,
  • Hiroshi Satoh

      Affiliations

    • Department of Environmental Health Sciences, Tohoku University, Graduate School of Medicine, 980-0875 Japan
  • ,
  • Kenichi Nagai

      Affiliations

    • Iwate Prefectural Ohasama Hospital, 028-3203 Japan

Received 15 November 2008 ,Revised 5 January 2009 ,Accepted 6 January 2009.

References 

  1. Behl C, Moosmann B. Oxidative nerve cell death in Alzheimer's disease and stroke: antioxidants as neuroprotective compounds. Biol Chem. 2002;383:521–536
  2. Paravicini TM, Drummond GR, Sobey CG. Reactive oxygen species in the cerebral circulation: physiological roles and therapeutic implications for hypertension and stroke. Drugs. 2004;64:2143–2157
  3. Slemmer JE, Shacka JJ, Sweeney MI, Weber JT. Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging. Curr Med Chem. 2008;15:404–414
  4. Ansari MA, Ahmad AS, Ahmad M, Salim S, Yousuf S, Ishrat T, et al. Selenium protects cerebral ischemia in rat brain mitochondria. Biol Trace Elem Res. 2004;101:73–86
  5. Salom JB, Perez-Asensio FJ, Burguete MC, Marin N, Pitarch C, Torregrosa G, et al. Single-dose ebselen does not afford sustained neuroprotection to rats subjected to severe focal cerebral ischemia. Eur J Pharmacol. 2004;495:55–62
  6. Yousuf S, Atif F, Ahmad M, Hoda MN, Khan MB, Ishrat T, et al. Selenium plays a modulatory role against cerebral ischemia-induced neuronal damage in rat hippocampus. Brain Res. 2007;1147:218–225
  7. Angelova EA, Atanassova PA, Chalakova NT, Dimitrov BD. Associations between serum selenium and total plasma homocysteine during the acute phase of ischaemic stroke. Eur Neurol. 2008;60:298–303
  8. Wei WQ, Abnet CC, Qiao YL, Dawsey SM, Dong ZW, Sun XD, et al. Prospective study of serum selenium concentrations and esophageal and gastric cardia cancer, heart disease, stroke, and total death. Am J Clin Nutr. 2004;79:80–85
  9. Koyama H, Terada A, Yoshida M, Nakada K, Abdulah R, Satoh H. Cysteine supplementation reduces the bioavailability of selenomethionine in mice. e-SPEN, Eur e-J Clin Nutr Metab. 2007;2:38–43
  10. Burk RF, Hill KE, Motley AK. Plasma selenium in specific and non-specific forms. Biofactors. 2001;14:107–114
  11. Hara S, Shoji Y, Sakurai A, Yuasa K, Himeno S, Imura N. Effects of selenium deficiency on expression of selenoproteins in bovine arterial endothelial cells. Biol Pharm Bull. 2001;24:754–759
  12. Small-Howard A, Morozova N, Stoytcheva Z, Forry EP, Mansell JB, Harney JW, et al. Supramolecular complexes mediate selenocysteine incorporation in vivo. Mol Cell Biol. 2006;26:2337–2346
  13. Schrauzer GN. The nutritional significance, metabolism and toxicology of selenomethionine. Adv Food Nutr Res. 2003;47:73–112
  14. Arteel GE, Mostert V, Oubrahim H, Briviba K, Abel J, Sies H. Protection by selenoprotein P in human plasma against peroxynitrite-mediated oxidation and nitration. Biol Chem. 1998;379:1201–1205
  15. McLean CW, Mirochnitchenko O, Claus CP, Noble-Haeusslein LJ, Ferriero DM. Overexpression of glutathione peroxidase protects immature murine neurons from oxidative stress. Dev Neurosci. 2005;27:169–175
  16. Koyama H, Omura K, Ejima A, Kasanuma Y, Watanabe C, Satoh H. Separation of selenium-containing proteins in human and mouse plasma using tandem high-performance liquid chromatography columns coupled with inductively coupled plasma-mass spectrometry. Anal Biochem. 1999;267:84–91
  17. Imai Y, Satoh H, Nagai K, Sakuma M, Sakuma H, Minami N, et al. Characteristics of a community-based distribution of home blood pressure in Ohasama in northern Japan. J Hypertens. 1993;11:1441–1449
  18. Sakuma M, Imai Y, Tsuji I, Nagai K, Ohkubo T, Watanabe N, et al. Predictive value of home blood pressure measurement in relation to stroke morbidity: a population-based pilot study in Ohasama, Japan. Hypertens Res. 1997;20:167–174
  19. Imai Y, Abe K, Sasaki S, Minami N, Munakata M, Sakuma H, et al. Clinical evaluation of semiautomatic and automatic devices for home blood pressure measurement: comparison between cuff-oscillometric and microphone methods. J Hypertens. 1989;7:983–990
  20. Watkinson JH. Fluorometric determination of selenium in biological material with 2,3-diaminonaphthalene. Anal Chem. 1966;38:92–97
  21. Rothman KJ, Greenland S, Lash TL. Case-control studies. In:  Rothman KJ,  Greenland S,  Lash TL editor. Modern epidemiology. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2008;p. 111–127
  22. Greenland S. Introduction to regression models. In:  Rothman KJ,  Greenland S,  Lash TL editor. Modern epidemiology. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2008;p. 381–417
  23. Aoki S. Igaku Tokei Kaiseki: reference manual. Tokyo: Igaku Shoin; 1989;
  24. Zhang XF, Attia J, D'Este C, Ma XY. The relationship between higher blood pressure and ischaemic, haemorrhagic stroke among Chinese and Caucasians: meta-analysis. Eur J Cardiovasc Prev Rehabil. 2006;13:429–437
  25. Kurth T, Everett BM, Buring JE, Kase CS, Ridker PM, Gaziano JM. Lipid levels and the risk of ischemic stroke in women. Neurology. 2007;68:556–562
  26. Amarenco P, Labreuche J, Touboul PJ. High-density lipoprotein–cholesterol and risk of stroke and carotid atherosclerosis: a systematic review. Atherosclerosis. 2008;196:489–496
  27. Bleys J, Navas-Acien A, Stranges S, Menke A, Miller ER, Guallar E. Serum selenium and serum lipids in US adults. Am J Clin Nutr. 2008;88:416–423
  28. Jossa F, Trevisan M, Krogh V, Farinaro E, Giumetti D, Fusco G, et al. Serum selenium and coronary heart disease risk factors in southern Italian men. Atherosclerosis. 1991;87:129–134
  29. Koyama H, Watanabe C, Satoh H, Hosokai H, Tamura S. Consistent relationship between selenium and apolipoprotein A-II concentrations in the sera of fasting middle-aged male abstainers and regular consumers of alcohol. Biol Trace Elem Res. 1995;50:33–42
  30. Abdulah R, Miyazaki K, Nakazawa M, Koyama H. Chemical forms of selenium for cancer prevention. J Trace Elem Med Biol. 2005;19:141–150
  31. Kryukov GV, Castellano S, Novoselov SV, Lobanov AV, Zehtab O, Guigo R, et al. Characterization of mammalian selenoproteomes. Science. 2003;300:1439–1443
  32. Burk RF, Hill KE. Selenoprotein P: an extracellular protein with unique physical characteristics and a role in selenium homeostasis. Annu Rev Nutr. 2005;25:215–235
  33. Herrman JL. The properties of a rat serum protein labelled by the injection of sodium selenite. Biochim Biophys Acta. 1977;500:61–70
  34. Motsenbocker MA, Tappel AL. A selenocysteine-containing selenium-transport protein in rat plasma. Biochim Biophys Acta. 1982;719:147–153
  35. Akesson B, Martensson B. Chromatography of selenoproteins in human serum using matrix-bound heparin. Int J Vitam Nutr Res. 1991;61:72–76
  36. Burk RF, Hill KE, Motley AK. Selenoprotein metabolism and function: evidence for more than one function for selenoprotein P. J Nutr. 2003;133:1517S–1520S
  37. Schweizer U, Schomburg L. Selenium, selenoproteins and brain function. In:  Hatfield DL,  Berry MJ,  Gladyshev VN editor. Selenium: its molecular biology and role in human health. 2nd ed. New York: Springer US; 2006;p. 233–248
  38. Schomburg L, Schweizer U, Holtmann B, Flohe L, Sendtner M, Kohrle J. Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues. Biochem J. 2003;370:397–402

PII: S0271-5317(09)00004-9

doi: 10.1016/j.nutres.2009.01.002

Nutrition Research
Volume 29, Issue 2 , Pages 94-99 , February 2009