Nutrition Research
Volume 29, Issue 4 , Pages 229-237 , April 2009

Short-chain fructo-oligosaccharides improve magnesium absorption in adolescent girls with a low calcium intake

  • Ellen G.H.M. van den Heuvel

      Affiliations

    • TNO Quality of Life, Biosciences Department, PO Box 360, 3700 AJ Zeist, The Netherlands
    • ,
  • Theo Muijs

      Affiliations

    • TNO Quality of Life, Biosciences Department, PO Box 360, 3700 AJ Zeist, The Netherlands
    • ,
  • Fred Brouns

      Affiliations

    • Cargill Research and Development Center, Department Health Nutrition, Havenstraat 84, B-1800 Vilvoorde, Belgium
    • Department Human Biology, Faculty of Health, Medicine and Life Sciences, P.O. Box 616, 6200 MD Maastricht, The Netherlands
    • ,
  • Henk F.J. Hendriks

      Affiliations

    • TNO Quality of Life, Biosciences Department, PO Box 360, 3700 AJ Zeist, The Netherlands
    • Corresponding Author InformationCorresponding author. Tel.: +31 3069 44294; fax: +31 3069 44928.

Received 27 November 2008 ,Revised 6 March 2009 ,Accepted 9 March 2009.

References 

  1. Scholz-Ahrens KE, Schaafsma G, Van den Heuvel EGHM, Schrezenmeir J. Effects of prebiotics on mineral metabolism. Am J Clin Nutr. 2001;73:459S–464S
  2. Coudray C, Feillet-Coudray C, Tressol JC, Gueux E, Thien S, Jaffrelo L, et al. Stimulatory effect of inulin on intestinal absorption of calcium and magnesium in rats is modulated by dietary calcium intakes; short- and long-term balance studies. Eur J Nutr. 2005;44:293–302
  3. Abrams SA, Griffin IJ, Hicks PD, Gunn SK. Pubertal girls only partially adapt to low dietary calcium intakes. J Bone Miner Res. 2004;19:759–763
  4. Van den Heuvel EGHM, Muys T, Van Dokkum W, Schaafsma G. Oligofructose stimulates calcium absorption in adolescents. Am J Clin Nutr. 1999;69:544–548
  5. Griffin IJ, Davila PM, Abrams SA. Non-digestible oligosaccharides and calcium absorption in girls with adequate calcium intakes. Br J Nutr. 2002;87:S187–S191
  6. Griffin IJ, Hicks PMD, Heaney RP, Abrams SA. Enriched chicory inulin increases calcium absorption mainly in girls with lower calcium absorption. Nutr Res. 2003;23:901–909
  7. Abrams SA, Griffin IJ, Hawthorne KM, Liang L, Gunn SK, Darlington G, et al. A combination of prebiotic short- and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents. Am J Clin Nutr. 2005;82:471–476
  8. Rémésy C, Levrat MA, Gamet L, Demigné C. Cecal fermentations in rats fed oligosaccharides (inulin) are modulated by dietary calcium level. Am J Physiol. 1993;264:G855–G862
  9. Ohta A, Ohtuki M, Takizawa T, Inaba H, Adachi T, Kimura S. Effects of fructooligosaccharides on the absorption of magnesium and calcium by cecectomized rats. Int J Vitam Nutr Res. 1994;64:316–323
  10. Ohta A, Ohtsuki M, Baba S, Takizawa T, Adachi T, Kimura S. Effects of fructooligosaccharides on the absorption of iron, calcium and magnesium in iron-deficient anemic rats. J Nutr Sci Vitaminol. 1995;41:281–291
  11. Ohta A, Ohtsuki M, Baba S, Adachi T, Sakata T, Sakaguchi E. Calcium and magnesium absorption from the colon and rectum are increased in rats fed fructooligosaccharides. J Nutr. 1995;125:2417–2424
  12. Delzenne N, Aertssens J, Verplaetse H, Roccaro M, Roberfroid M. Effect of fermentable fructo-oligosaccharides on mineral, nitrogen and energy digestive balance in the rat. Life Sci. 1995;57:1579–1587
  13. Coudray C, Bellanger J, Castiglia-Delavaud C, Rémésy C, Vermorel V, Rayssignuier Y. Effect of soluble or partly soluble dietary fibres supplementation on absorption and balance of calcium, magnesium, iron and zinc in healthy young men. Eur J Clin Nutr. 1997;51:375–380
  14. Ohta A, Baba S, Takizawa T, Adachi T. Effects of fructooligosaccharides on the absorption of magnesium in the magnesium-deficient rat model. J Nutr Sci Vitam. 1994;40:171–180
  15. Tahiri M, Tressol JC, Arnaud J, et al. Five-week intake of short-chain fructo-oligosaccharides increases intestinal absorption and status of magnesium in postmenopausal women. J Bone Miner Res. 2001;16:2152–2160
  16. Tahiri M, Tressol JC, Arnaud J, et al. Effect of short chain fructooligosaccharides on intestinal calcium absorption and calcium status in postmenopausal women: a stable-isotope study. Am J Clin Nutr. 2003;77:449–457
  17. Van den Heuvel EGHM, Schaafsma G, Muys T, Van Dokkum W. Nondigestible oligosaccharides do not interfere with calcium and nonheme-iron absorption in young, healthy men. Am J Clin Nutr. 1998;67:445–452
  18. Ohta A, Motohashi Y, Ohtsuki M, Hirayama M, Adachi T, Sakuma K. Dietary fructooligosaccharides change the concentration of calbindin-D9K differently in the mucosa of the small and large intestine of rats. J Nutr. 1998;128:934–939
  19. Chonan O, Matsumoto K, Watanuki M. Effect of galactooligosaccharides on calcium absorption and preventing bone loss in ovariectomized rats. Biosci Biotech Biochem. 1995;59:236–239
  20. Löwik MRH, Hulshof KFAM, van der Heijden LJM, Brussaard JH, Burema J, Kistemaker C, et al. Changes in the diet in the Netherlands: 1987-1988 to 1992. Int J Food Sci and Nutr. 1998;49:S1–S64
  21. Yergey AL, Abrams SA, Vieira NE, Aldroubi A, Marini J, Sidbury JB. Determination of fractional absorption of dietary calcium in humans. J Nutr. 1994;124:674–682
  22. Abrams A, Wen JP. Methodologies for using stable isotopes to assess magnesium absorption and secretion in children. J Am Coll Nutr. 1999;18:30–35
  23. NEVO Foundation . Dutch Food Composition Table 1996. In: The Hague: The Netherlands Nutrition Centre; 1996;
  24. Bingham SA, Cummings JH. The use of 4-aminobenzoic acid as a marker to validate the completeness of 24 h urine collections in man. Clin Sci. 1983;64:629–635
  25. Bingham SA, Cummings JH. The use of creatinine output as a check on the completeness of 24-hour urine collections. Hum Nutr Clin Nutr. 1985;39C:343–353
  26. Luten JB, Muijs T, Van Dokkum W. The determination of stable isotope ratio of zinc, copper, iron in faeces and calcium in urine by ICP-MS. In:  Schlemmer U editors. Bioavailability ′93. Nutritional, chemical and food processing implications of nutrient availability. Karlsruhe: Bundesforschungsanstalt für Ernährung; 1993;p. 161–168
  27. Schuette S, Vereault D, Ting BT, Janghorbani M. Accurate measurement of stable isotopes of magnesium in biological materials with inductively coupled plasma mass spectrometry. Analyst. 1988;113:1837–1842
  28. Jongen MJM, Van der Vijgh WJF, Willems HJJ, Netelenbos JC. Analysis for 1,25-dihydroxyvitamin D in human plasma, after a liquid chromatographic purification procedure, with a modified competitive protein-binding assay. Clin Chem. 1981;27:444–450
  29. Bouillon R, van Assche FA, van Baelen H, Heyns W, de Moor P. Influence of vitamin D-binding protein on the serum concentration of 1,25 dihydroxyvitamin D3. J Clin Invest. 1981;67:589–596
  30. Belstra BA, Flowers WL, Croom WJ, Degroot J, See MT. Urinary excretion of collagen degradation markers by sows during postpartum uterine involution. Anim Reprod Sci. 2005;85:131–145
  31. Statistical Analyses Systems. SAS/STAT User's Guide version 6, 4th ed., vol. 2. Cary (NC): SAS Institute Inc; 1994.
  32. Martin AD, Bailey DA, McKay HA, Whiting S. Bone mineral and calcium accretion during puberty. Am J Clin Nutr. 1997;66:611–615
  33. Lee WT, Leung SS, Leung DM, Tsang HS, Lau J, Cheng JC. A randomized double-blind controlled calcium supplementation trial, and bone and height acquisition in children. Br J Nutr. 1995;74:125–139
  34. Wood RJ. Searching for the determinants of intestinal calcium absorption. Am J Clin Nutr. 2000;72:675–676
  35. Raschka L, Daniel H. Diet composition and age determine the effects of inulin-type fructans on intestinal calcium absorption in rat. Eur J Nutr. 2005;44:360–364
  36. Van den Heuvel EGHM, Muijs T, Van Dokkum W, Schaafsma G. Lactulose stimulates calcium absorption in postmenopausal women. J Bone Miner Res. 1999;14:1211–1216
  37. Bouhnik Y, Raskine L, Simoneau G, et al. The capacity of non-digestible carbohydrates to stimulate fecal bifidobacteria in healthy humans: a double-blind, randomized, placebo-controlled, parallel-group, dose-response relation study. Am J Clin Nutr. 2004;80:1658–1664
  38. Younes H, Demigné C, Rémésy C. Acidic fermentation in the caecum increases absorption of calcium and magnesium in the large intestine of the rat. Br J Nutr. 1996;75:301–314
  39. Hardwick LL, Jones MR, Brautbar N, Lee DB. Site and mechanism of intestinal magnesium absorption. Miner Electrolyte Metab. 1990;16:174–180
  40. Kayne LH, Lee DB. Intestinal magnesium absorption. Miner Electrolyte Metab. 1993;19:210–217
  41. Lopez HW, Coudray C, Levrat-Verny M-A, Feillet-Coudray C, Demigné C, Rémésy C. Fructooligosaccharides enhance mineral apparent absorption and counteract the deleterious effects of phytic acid on mineral homeostasis in rats. J Nutr Biochem. 2000;11:500–508
  42. Scharrer E, Lutz T. Effects of short chain fatty acids and K on absorption of Mg and other cations by the colon and caecum. Z Ernährungswiss. 1990;29:162–168
  43. Matkovic V, Badenhop NE, Ilich JZ. Trace element and mineral nutrition in adolescents. In:  Bogden JD,  Klevay LM editor. Clinical Nutrition of the essential trace elements and minerals: The guide for health professionals. Totowa (NJ): Humana Press Inc.; 2000;p. 153–182
  44. Takahara S, Morohashi T, Sano T, Ohta A, Yamada S, Sasa R. Fructooligosaccharide consumption enhances femoral bone volume and mineral concentration in rats. J Nutr. 2000;130:1792–1795
  45. Szulc P, Seeman E, Delmas PD. Biochemical measurements of bone turnover in children and adolescents. Osteoporosis Int. 2000;11:281–294
  46. Tohmé JF, Seibel MJ, Silverberg SJ, Robins SP, Bilezikian JP. Biochemical markers of bone metabolism. Z Rheumatol. 1991;50:144–151

PII: S0271-5317(09)00038-4

doi: 10.1016/j.nutres.2009.03.005

Nutrition Research
Volume 29, Issue 4 , Pages 229-237 , April 2009

Article Tools

* Image Usage & Resolution