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Nutrition Research
Volume 29, Issue 4
, Pages 221-228
, April 2009
High-dose vitamin K supplementation reduces fracture incidence in postmenopausal women: a review of the literature
References
- . Vitamin K–dependent carboxylation. Vitam Horm. 2008;78:131–156
- . The vitamin K–dependent carboxylase. Annu Rev Nutr. 2005;25:127–149
- . The physiology of vitamin K nutriture and vitamin K–dependent protein function in atherosclerosis. J Thromb Haemost. 2004;2:2118–2132
- The circulating inactive form of matrix Gla protein (ucMGP) as a biomarker for cardiovascular calcification. J Vasc Res. 2008;45:427–436
- Post-translational modifications regulate matrix Gla protein function: importance for inhibition of vascular smooth muscle cell calcification. J Thromb Haemost. 2007;5:2503–2511
- . Effects of the blood coagulation vitamin K as an inhibitor of arterial calcification. Thromb Res. 2008;122:411–417
- . Osteocalcin and matrix Gla protein: vitamin K–dependent proteins in bone. Physiol Rev. 1989;69:990–1047
- . Vitamin K2 enhances osteocalcin accumulation in the extracellular matrix of human osteoblasts in vitro. J Bone Miner Res. 1997;12:431–438
- . Vitamin K. Lancet. 1995;345:229–234
- . Role of vitamin K in bone metabolism. Annu Rev Nutr. 1995;15:1–22
- Vitamin K2 regulation of bone homeostasis is mediated by the steroid and xenobiotic receptor SXR. J Biol Chem. 2003;278:43919–43927
- . Prevention and management of osteoporosis. World Health Organ Tech Rep Ser. 2003;921:86–109
- . Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials. Arch Intern Med. 2006;166:1256–1261
- Conversion of phylloquinone (Vitamin K1) into menaquinone-4 (Vitamin K2) in mice: two possible routes for menaquinone-4 accumulation in cerebra of mice. J Biol Chem. 2008;283:11270–11279
- . Vitamin K–containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7. Blood. 2007;109:3279–3283
- Two-year randomized controlled trial of vitamin K1 (phylloquinone) and vitamin D3 plus calcium on the bone health of older women. J Bone Miner Res. 2007;22:509–519
- Vitamin K supplementation in postmenopausal women with osteopenia (ECKO trial): a randomized controlled trial. PLos Med. 2008;5:e196
- . Vitamin K2 supplementation improves hip bone geometry and bone strength indices in postmenopausal women. Osteoporos Int. 2007;18:963–972
- . Effect of vitamin K supplementation on bone loss in elderly men and women. J Clin Endocrinol Metab. 2008;93:1217–1223
- Vitamin K1 supplementation retards bone loss in postmenopausal women between 50 and 60 years of age. Calcif Tissue Int. 2003;73:21–26
- . Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis. J Bone Miner Res. 2000;15:515–521
- Randomized controlled study on the prevention of osteoporotic fractures (OF Study): a phase IV clinical study of 15-mg menatetrenone capsules. J Bone Miner Metab. 2009;27:66–75
- . Clinical evaluation of soft capsule menatetrenone (Ea-0167) in the treatment of osteoporosis. Late Phase II Dose Study. J New Remedies Clinics. 1992;41:1249–1279[in Japanese]
- . Oxford-centre evidence based medicine. Levels of evidence and grades of recommendation. http://www.cebm.net/levels_of_evidence.asp
- Increased bone formation in osteocalcin-deficient mice. Nature. 1996;382:448–452
- . Cellular “sensing" of extracellular calcium (Ca(2+)(0)): emerging roles in regulating diverse physiological functions. Cell Signal. 2000;12:361–366
- Identification of a novel extracellular cation-sensing G-protein–coupled receptor. J Biol Chem. 2005;280:40201–40209
- Dietary vitamin K intakes are associated with hip fracture but not with bone mineral density in elderly men and women. Am J Clin Nutr. 2000;71:1201–1208
- Japanese fermented soybean food as the major determinant of the large geographic difference in circulating levels of vitamin K2: possible implications for hip-fracture risk. Nutrition. 2001;17:315–321
- . Serum undercarboxylated osteocalcin is a marker of the risk of hip fracture in elderly women. J Clin Invest. 1993;91:1769–1774
- . Serum undercarboxylated osteocalcin is a marker of the risk of hip fracture: a three year follow-up study. Bone. 1996;18:487–488
- . Undercarboxylated osteocalcin measured with a specific immunoassay predicts hip fracture in elderly women: the EPIDOS Study. J Clin Endocrinol Metab. 1997;82:719–724
- Strong prediction of fractures among older adults by the ratio of carboxylated to total serum osteocalcin. J Bone Miner Res. 2000;15:2473–2478
- . Vitamin K intake and hip fractures in women: a prospective study. Am J Clin Nutr. 1999;69:74–79
- Low plasma phylloquinone concentration is associated with high incidence of vertebral fracture in Japanese women. J Bone Miner Metab. 2008;26:79–85
- . Osteoporosis prevention, diagnosis, and therapy. JAMA. 2001;285:785–795
- . Risk of hip fracture derived from relative risks: an analysis applied to the population of Sweden. Osteoporos Int. 2000;11:120–127
- A functional single nucleotide polymorphism in the vitamin-K–dependent gamma-glutamyl carboxylase gene (Arg325Gln) is associated with bone mineral density in elderly Japanese women. Bone. 2007;40:451–456
- . The inhibitory effect of vitamin K2 (menatetrenone) on bone resorption may be related to its side chain. Bone. 1995;16:179–184
- . Menatetrenone inhibits bone resorption partly through inhibition of PGE2 synthesis in vitro. J Bone Miner Res. 1993;8:535–542
- Vitamin K treatment reduces undercarboxylated osteocalcin but does not alter bone turnover, density or geometry in healthy postmenopausal North American women. J Bone Miner Res. 2008;[Online publication]
- . Changes in the supporting muscles of the fractured hip in elderly women. Bone. 2002;30:325–330
- Effect of vitamin D on falls: a meta-analysis. JAMA. 2004;291:1999–2006
- . Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. JAMA. 2005;293:2257–2264
- . Vitamin D insufficiency in Japanese populations: from the viewpoint of the prevention of osteoporosis. J Bone Miner Metab. 2006;24:1–6
- . Relationship between serum 25-hydroxyvitamin D and bone resorption markers in vitamin D insufficiency. Bone. 2002;31:626–630
PII: S0271-5317(09)00057-8
doi: 10.1016/j.nutres.2009.03.012
© 2009 Elsevier Inc. All rights reserved.
Next »
Nutrition Research
Volume 29, Issue 4
, Pages 221-228
, April 2009
