Nutrition Research
Volume 29, Issue 6 , Pages 414-418 , June 2009

Chia seed does not promote weight loss or alter disease risk factors in overweight adults

  • David C. Nieman

      Affiliations

    • Department of Health, Leisure, and Exercise Science Appalachian State University, Boone, NC 28608, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 828 262 6318; fax: +1 828 262 3138.
    • ,
  • Erin J. Cayea

      Affiliations

    • Department of Health, Leisure, and Exercise Science Appalachian State University, Boone, NC 28608, USA
    • ,
  • Melanie D. Austin

      Affiliations

    • Department of Health, Leisure, and Exercise Science Appalachian State University, Boone, NC 28608, USA
    • ,
  • Dru A. Henson

      Affiliations

    • Department of Biology, Appalachian State University, Boone, NC 28608, USA
    • ,
  • Steven R. McAnulty

      Affiliations

    • Department of Health, Leisure, and Exercise Science Appalachian State University, Boone, NC 28608, USA
    • ,
  • Fuxia Jin

      Affiliations

    • Department of Health, Leisure, and Exercise Science Appalachian State University, Boone, NC 28608, USA

Received 11 March 2009 ,Revised 26 May 2009 ,Accepted 28 May 2009.

References 

  1. Burdge GC. Metabolism of alpha-linolenic acid in humans. Prostaglandins Leukot Essent Fatty Acids. 2006;75:161–168
  2. Arterburn LM, Hall EB, Oken H. Distribution, interconversion, and dose response of n-3 fatty acids in humans. Am J Clin Nutr. 2006;83(6 Suppl):1467S–1476S
  3. Harper CR, Edwards MJ, DeFilippis AP, Jacobson TA. Flaxseed oil increases the plasma concentrations of cardioprotective (n-3) fatty acids in humans. J Nutr. 2006;136:83–87
  4. Whelan J, Rust C. Innovative dietary sources of n-3 fatty acids. Annu Rev Nutr. 2006;26:75–103
  5. Balk EM, Lichtenstein AH, Chung M, Kupelnick B, Chew P, Lau J. Effects of omega-3 fatty acids on serum markers of cardiovascular disease risk: a systematic review. Atherosclerosis. 2006;189:19–30
  6. Dodin S, Cunnane SC, Mâsse B, Lemay A, Jacques H, Asselin G, et al. Flaxseed on cardiovascular disease markers in healthy menopausal women: a randomized, double-blind, placebo-controlled trial. Nutrition. 2008;24:23–30
  7. Nelson TL, Stevens JR, Hickey MS. Inflammatory markers are not altered by an eight week dietary alpha-linolenic acid intervention in healthy abdominally obese adult males and females. Cytokine. 2007;38:101–106
  8. Chicco AG, D'Alessandro ME, Hein GJ, Oliva ME, Lombardo YB. Dietary chia seed (Salvia hispanica L.) rich in alpha-linolenic acid improves adiposity and normalises hypertriacylglycerolaemia and insulin resistance in dyslipaemic rats. Br J Nutr. 2008;20:1–10
  9. Ayerza R, Coates W. Effect of dietary alpha-linolenic fatty acid derived from chia when fed as ground seed, whole seed and oil on lipid content and fatty acid composition of rat plasma. Ann Nutr Metab. 2007;51:27–34
  10. Ayerza R, Coates W, Lauria M. Chia seed (Salvia hispanica L.) as an omega-3 fatty acid source for broilers: influence on fatty acid composition, cholesterol and fat content of white and dark meats, growth performance, and sensory characteristics. Poult Sci. 2002;81:826–837
  11. Reyes-Caudillo E, Tecante A, Valdivia-Lόpez MA. Dietary fiber content and antioxidant activity of phenolic compounds in Mexican chia (Salvia hispanica L.) seeds. Food Chem. 2008;107:656–663
  12. Vuksan V, Whitham D, Sievenpiper JL, Jenkins AL, Rogovik AL, Bazinet RP, et al. Supplementation of conventional therapy with the novel grain Salba (Salvia hispanica L.) improves major and emerging cardiovascular risk factors in type 2 diabetes: results of a randomized controlled trial. Diabetes Care. 2007;30:2804–2810
  13. Vázquez-Ovando A, Rosado-Rubio G, Chel-Guerrero L, Betancur-Ancona D. Physiochemical properties of a fibrous fraction from chia (Salvia hispanica L.). LWT-Food Sci Technol. 2008;42:168–173
  14. Howarth NC, Huang TT, Roberts SB, Lin BH, McCrory MA. Eating patterns and dietary composition in relation to BMI in younger and older adults. Int J Obes (Lond). 2007;31:675–684
  15. Parra D, Ramel A, Bandarra N, Kiely M, Martínez JA, Thorsdottir I. A diet rich in long chain omega-3 fatty acids modulates satiety in overweight and obese volunteers during weight loss. Appetite. 2008;51:676–680
  16. U.S. Department of Agriculture, Agricultural, Research Service. 2008. Nutrient intakes from food: mean amounts consumed per individual, one day, 2005-2006.
  17. Harper CR, Edwards MC, Jacobson TA. Flaxseed oil supplementation does not affect plasma lipoprotein concentration or particle size in human subjects. J Nutr. 2006;136:2844–2848
  18. Austria JA, Richard MN, Chahine MN, Edel AL, Malcolmson LJ, Dupasquier CM, et al. Bioavailability of alpha-linolenic acid in subjects after ingestion of three different forms of flaxseed. J Am Coll Nutr. 2008;27:214–221

PII: S0271-5317(09)00089-X

doi: 10.1016/j.nutres.2009.05.011

Nutrition Research
Volume 29, Issue 6 , Pages 414-418 , June 2009

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