Nutrition Research
Volume 30, Issue 1 , Pages 66-73 , January 2010

Tomato powder is more protective than lycopene supplement against lipid peroxidation in rats

  • Ali A. Alshatwi

      Affiliations

    • Department of Food Science and Nutrition, King Saud University, Riyadh 11451, Saudi Arabia
    • Corresponding Author InformationCorresponding author. Tel.: +1 301 405 2143; fax: +1 301 314 3313; or Tel.: +996 1 467 7122; fax: +996 1 467 8394.
    • ,
  • Manal A. Al Obaaid

      Affiliations

    • Department of Food Science and Nutrition, King Saud University, Riyadh 11451, Saudi Arabia
    • ,
  • Sahar A. Al Sedairy

      Affiliations

    • Department of Food Science and Nutrition, King Saud University, Riyadh 11451, Saudi Arabia
    • ,
  • Abdullah H. Al-Assaf

      Affiliations

    • Department of Food Science and Nutrition, King Saud University, Riyadh 11451, Saudi Arabia
    • ,
  • Jun Jun Zhang

      Affiliations

    • Department of Nutrition and Food Science, University of Maryland, College Park, MD 20742, USA
    • ,
  • Kai Y. Lei

      Affiliations

    • Department of Nutrition and Food Science, University of Maryland, College Park, MD 20742, USA
    • Center of Excellence for Biotechnology Research, King Saud University, Riyadh 11451, Saudi Arabia
    • Corresponding Author InformationCorresponding author. Tel.: +1 301 405 2143; fax: +1 301 314 3313; or Tel.: +996 1 467 7122; fax: +996 1 467 8394.

Received 24 August 2009 ,Revised 31 October 2009 ,Accepted 14 December 2009.

References 

  1. Rao AV, Agarwal S. Bioavailability and in vivo antioxidant properties of lycopene from tomato products and their possible role in the prevention of cancer. Nutr Cancer. 1998;31:199–203
  2. Heber D, Lu QY. Overview of mechanisms of action of lycopene. Exp Biol Med. 2002;227:920–923
  3. Di Mascio P, Kaiser S, Sies H. Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Arch Biochem Biophys. 1989;274:532–538
  4. Cohen JH, Kristal AR, Stanford JL. Fruit and vegetable intakes and prostate cancer risk. J Natl Cancer Inst. 2000;92:61–68
  5. Kihlstrom M, Salminen A, Vihko V. Chronic hydrogen peroxide intake and peroxide metabolizing enzyme activities in some tissues of mice and rats. Experientia. 1986;42:1018–1020
  6. Ostrowska J, Luczaj W, Kasacka I, Rozanski A, Skrzydlewska E. Green tea protects against ethanol-induced lipid peroxidation in rat organs. Alcohol. 2004;32:25–32
  7. Richmond N. Preparation and properties of a cholesterol oxidase from Nocardia sp and its application to the enzymatic assay of total cholesterol in serum. J Clin Chem. 1973;19:1350–1356
  8. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499–502
  9. Trinder P. Enzymatic method of triglycerides. Ann Clin Biochem. 1969;6:24–27
  10. Satoh K. Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method. Clin Chim Acta. 1978;90:37–43
  11. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979;95:351–358
  12. Boileau TW, Clinton SK, Erdman JW. Tissue lycopene concentrations and isomer patterns are affected by androgen status and dietary lycopene concentration in male F344 rats. J Nutr. 2000;130:1613–1618
  13. Daniel WW. Biostatistics. A foundation for Analysis in health sciences. Sixth edition. New York: John Wiley and Sons, Inc.; 1995;
  14. Paetau I, Khachik F, Brown ED, Beecher GR, Kramer TR, Chittams J, et al. Chronic ingestion of lycopene-rich tomato juice or lycopene supplements significantly increases plasma concentrations of lycopene and related tomato carotenoids in humans. Am J Clin Nutr. 1998;68:1187–1195
  15. Shi J, Kakuda Y, Yeung D. Antioxidative properties of lycopene and other carotenoids from tomatoes: synergistic effects. Biofactors. 2004;21:203–210
  16. Loreto F, Velikova V. Isoprene produced by leaves protects the photosynthetic apparatus against ozone damage, quenches ozone products, and reduces lipid peroxidation of cellular membranes. Plant Physiol. 2001;127:1781–1787
  17. Meng X, Reeves WB. Effects of chloride channel inhibitors on H(2)O(2)-induced renal epithelial cell injury. Am J Physiol Renal Physiol. 2000;278:F83–F90
  18. Fang YZ, Yang S, Wu G. Free radicals, antioxidants, and nutrition. Nutrition. 2002;18:872–879
  19. Bose KS, Agrawal BK. Effect of lycopene from cooked tomatoes on serum antioxidant enzymes, lipid peroxidation rate and lipid profile in coronary heart disease. Singapore Med J. 2007;48:415–420
  20. Kim Y, DiSilvestro R, Clinton S. Effects of lycopene-beadlet or tomato-powder feeding on carbon tetrachloride-induced hepatotoxicity in rats. Phytomedicine. 2004;11:152–156
  21. United States national Agriculture Library {online} . USDA Nutrient data bank. http://www.nal.gov2004;
  22. Shi J, Le MM. Lycopene in tomatoes: chemical and physical properties affected by food processing. Crit Rev Biotechnol. 2000;20(4):293–334
  23. Tonucci LH, Holden JM, Beecher GR, Khachik F, Davis CS, Mulokzi G. Carotenoid content of thermally processed tomato-based food products. J Agric Food Chem. 1995;43(3):579–586
  24. Campbell JK, Canene-Adams K, Lindshield BL, Boileau TW, Clinton SK, Erdman JW. Tomato phytochemicals and prostate cancer risk. J Nutr. 2004;134(12 Suppl):3486S–3492S
  25. Aly E, Hassan F. The effect of tomato pomace and paste on some biochemical aspects in serum and liver and antioxidant status of hypercholesterolemic rats. Bull Nat Nutr Inst. 2004;25:1–21
  26. Misra R, Mangi S, Joshi S, Mittal S, Gupta SK, Pandey RM. LycoRed as an alternative to hormone replacement therapy in lowering serum lipids and oxidative stress markers: a randomized controlled clinical trial. J Obstet Gynaecol Res. 2006;32:299–304
  27. Ahuja KD, Pittaway JK, Ball MJ. Effects of olive oil and tomato lycopene combination on serum lycopene, lipid profile, and lipid oxidation. Nutrition. 2006;22:259–265
  28. Silaste ML, Alfthan G, Aro A, Kesaniemi YA, Horkko S. Tomato juice decreases LDL cholesterol levels and increases LDL resistance to oxidation. Br J Nutr. 2007;98(6):1251–1258
  29. Bobek P. Dietary tomato and grape pomace in rats: effect on lipids in serum and liver, and on antioxidant status. Br J Biomed Sci. 1999;56:109–113
  30. Hsu YM, Lai CH, Chang CY, Fan CT, Chen CT, Wu CH. Characterizing the lipid-lowering effects and antioxidant mechanisms of tomato paste. Biosci Biotechnol Biochem. 2008;72:677–685
  31. Rao AV. Lycopene, tomatoes, and the prevention of coronary heart disease. Exp Biol Med (Maywood). 2002;227:908–913
  32. Fuhrman B, Elis A, Aviram M. Hypocholesterolemic effect of lycopene and beta-carotene is related to suppression of cholesterol synthesis and augmentation of LDL receptor activity in macrophages. Biochem Biophys Res Commun. 1997;233:658–662

PII: S0271-5317(09)00252-8

doi: 10.1016/j.nutres.2009.12.002

Nutrition Research
Volume 30, Issue 1 , Pages 66-73 , January 2010

Article Tools

* Image Usage & Resolution